Abstract: This study focuses on dissimilar steel joints of A514/Q355ME, using flux-cored wire and solid wire for welding experiments. A systematic comparison was conducted on the microstructure and mechanical properties of the welded joints produced by the two types of welding wires. The results show that under the same welding process, there are significant differences in the morphological features and grain size of the joints welded with different wires. Crack resistance tests using the Lehigh method indicate that both joints exhibit comparable crack resistance, meeting the application requirements.The joint welded with flux-cored wire shows slightly higher yield strength and tensile strength compared to the solid wire joint, while their elongation is similar. In impact tests at -40°C, the impact energy at the weld of the solid wire joint reaches 172 J, which is significantly higher than the 68 J of the flux-cored wire joint. The fatigue limit of the solid wire joint reaches 390 MPa, exceeding the 370 MPa of the flux-cored wire joint.Overall, both types of joints meet engineering application requirements, but the appropriate welding material should be selected according to specific service conditions.