Abstract: Nodular cast iron is a kind of traditional steel material which is widely used in many important industrial fields such as rail vehicles and ship engine cylinders. But it is difficult to be repaired due to great cracking tendency during repairing process. It is difficult to find a kind of repairing material with an excellent combination of phase structure and mechanical properties. In the present research, a kind of new-type Fe-Inconel625 alloy powder had been applied to the laser cladding process of nodular cast iron. The microstructure and phase evolution were determined and the Micro hardness had been also researched. Optical microscope (OM) and Scanning electron microscopy (SEM) were used to identify the microstructure. Energy dispersive microanalysis (EDS), X-ray diffraction (XRD) were used to determine phase types of the claddings and interface zones. The results showed that the cladding layer has no porosity, cracks and other defects, and the interface and cladding layer have good hardness