Abstract: Refractory high-entropy alloys (RHEAs) have attracted much attention in recent years due to their excellent high-temperature mechanical properties. However, poor room-temperature ductility and high density are still the main factors that limit its industrial applications. A Ti₆₀Nb₁₂Mo₁₂Ta₁₂W₄ refractory high-entropy alloy with a theoretical density of only 7.708g/cm³ is prepared by a combination of mechanical alloying and discharge plasma sintering. The effects of sintering temperature on the microstructure and mechanical properties of the alloy are studied. The results show that the alloy phase structure is composed of BCC phase (BCC1 phase and BCC2 phase) and a very small amount of FCC precipitated phase. At room temperature, the alloy sintered at 1600℃ obtains the highest compressive peak stress and the best plasticity (2542MPa and 9.8%), while the alloy still maintains high compressive performance at 1000℃, and the highest peak stress can reach 419MPa.This study will provide some reference for the preparation, characterization, and further industrial application of RHEA.